Probiotics + Hyaluronic Acid 30 Billion CFU 60 Veggie Capsules

Hyaluronic acid is a polysaccharide found in the skin's dermis and in joint fluid, a moisturising compound that holds several hundred times its own weight in water. Women's probiotic products combine strains for women's wellness, such as Lactobacillus, with oral hyaluronic acid to support both skin hydration and women's daily condition.

Ingested hyaluronic acid has been reported to be partly broken down by gut bacteria into low-molecular oligosaccharides and absorbed, with some distributed to skin tissue. A proposed mechanism is that these breakdown products stimulate hyaluronic acid synthesis and cell proliferation in fibroblasts, contributing to stratum corneum hydration and the skin barrier (reduced transepidermal water loss). Women's probiotics may help maintain a Lactobacillus-dominant state, the main bacteria of the vaginal environment, and a mildly acidic pH, but whether orally taken strains actually colonise varies by strain.

1. In a 12-week double-blind RCT of 40 healthy Asian adults aged 35–64 (2021), the group taking hyaluronic acid 120 mg/day showed improvements in wrinkle assessment, stratum corneum hydration, transepidermal water loss and skin elasticity versus placebo.
2. In a 12-week double-blind RCT of 150 healthy adults (2025), sodium hyaluronate at 120 mg/day was associated with increased skin hydration and elasticity, reduced transepidermal water loss and eye-area wrinkle depth, and increased epidermal thickness and natural moisturising factor (NMF), with smaller changes observed at 60 mg/day.
3. A review (2014) summarised the absorption and skin distribution of oral hyaluronic acid, the mechanism by which it promotes hyaluronic acid synthesis in fibroblasts, and findings of increased skin hydration in RCTs of people with dry skin.
4. In a 2-week RCT of 50 healthy women without vaginal discomfort (2023), a Lactobacillus-dominant vaginal microbiota and appropriate pH remained stable during oral probiotic intake (L. acidophilus La-14, L. rhamnosus HN001), with no safety issues reported (vaginal colonisation by the ingested strains was below the detection limit).

1. RCTHsu TF et al. Oral Hyaluronan Relieves Wrinkles and Improves Dry Skin: A 12-Week Double-Blinded, Placebo-Controlled Study Nutrients. 2021. PMID 34203487
2. RCTDolečková I et al. Oral sodium hyaluronate improves skin hydration, barrier function and signs of aging: a randomized, double-blind, placebo-controlled trial in 150 healthy adults Sci Rep. 2025. PMID 41422283
3. reviewKawada C et al. Ingested hyaluronan moisturizes dry skin Nutr J. 2014. PMID 25014997
4. RCTLyra A et al. A Healthy Vaginal Microbiota Remains Stable during Oral Probiotic Supplementation: A Randomised Controlled Trial Microorganisms. 2023. PMID 36838464

Probiotics are live microorganisms that provide a benefit when consumed in adequate amounts, mainly strains from the Lactobacillus and Bifidobacterium groups. Multi-strain products combine several strains, and their content is expressed in CFU (colony-forming units).

Ingested beneficial bacteria produce organic acids such as lactic and acetic acid and short-chain fatty acids in the gut, lowering intestinal pH and creating an environment in which unwanted bacteria find it harder to settle. Short-chain fatty acids are an energy source for intestinal epithelial cells and are known to help maintain the intestinal mucosal barrier (tight junctions) and gut motility. They can also interact with gut-associated lymphoid tissue (GALT), influencing immune signals such as secretory IgA and cytokine balance. Effects vary with strain, dose and duration of intake, and differ widely between individuals.

1. A Cochrane systematic review (2022, 23 RCTs, 6,950 participants) reported that, versus placebo, probiotic groups had a lower proportion of people experiencing at least one episode of acute upper respiratory symptoms (RR 0.76) and a shorter average episode duration (about 1.2 days shorter) (low to moderate certainty of evidence).
2. A meta-analysis of 20 RCTs in healthy children and adults (2014) reported that groups taking Lactobacillus and Bifidobacterium had fewer days with respiratory symptoms and shorter episodes (by about 0.77 days) than placebo, as well as fewer days absent from school or work.
3. A meta-analysis of 15 RCTs in adults with irregular bowel movements (2020) found that probiotics shortened whole-gut transit time by an average of about 13.8 hours and increased weekly bowel movements by about one, with improvements in stool consistency and bloating reported particularly for multi-strain products of two or more strains.

1. meta-analysisZhao Y et al. Probiotics for preventing acute upper respiratory tract infections Cochrane Database Syst Rev. 2022. PMID 36001877
2. meta-analysisKing S et al. Effectiveness of probiotics on the duration of illness in healthy children and adults who develop common acute respiratory infectious conditions: a systematic review and meta-analysis Br J Nutr. 2014. PMID 24780623
3. meta-analysisZhang C et al. Meta-analysis of randomized controlled trials of the effects of probiotics on functional constipation in adults Clin Nutr. 2020. PMID 32005532